Today, most athletes for regenerative therapy using Clomid – buy nolvadex online. At the same time, there is no equally effective drug – Nolvadex. Find out what are the differences between Clomid and Nolvadex.
Many athletes prefer Clomid Nolvadex for reasons not completely understood. In this article we will try to give an objective assessment of these drugs and find out which one is more effective.
The difference between Clomid and Nolvadex
It is difficult to explain why athletes can see significant differences between the two drugs. This should not be at least for the reason that they belong to a class of anti-estrogens group trifeniletilenov. They have a similar chemical structure and have similar properties. Details
Clomid and Nolvadex classified as selective modulators of estrogen receptors of type that have mixed agonistic and antagonistic properties. Simply put, in some tissues drugs capable of blocking the female hormones by binding of the receptors, while others manifest themselves as estrogens.
The male body preparations prevent adverse effects of female hormones on the hypothalamus, which leads to faster production of luteinizing hormone and subsequently testosterone. However, many athletes believe that it is able to do just Clomid.
Even in the last century it was carried out large-scale study that compared the drugs. In the experiment, took part, as a young and healthy man, and suffering from oligospermia (low sperm count in the semen). However, in this article are more interested in healthy men.
Nolvadex Subjects received during 10 days in an amount of 20 milligrams. It is possible to increase the level of the male hormone by 140 percent. When using Clomid similar result was achieved when using a dosage of 150 milligrams. Simply put, the ratio of the result of price were not in favor of Clomid.
But this study also revealed another interesting result in the study of the impact of drugs on the levels of GnRH. The results were quite the opposite. As is known, the higher the pituitary sensitivity to GnRH, the stronger the synthesis of LH.
When using Nolvadex became more sensitive the pituitary GnRH, while after using Clomid, this figure fell. Initially, the experiment lasted 10 days, after which it was extended. For long-term use of Nolvadex showed even more outstanding results compared to Clomid. No one is saying that Clomid is not effective, just was the best Nolvadex.
At the beginning of this article we said that drugs are structurally similar, but their power of influence is different in different tissues. According to the research results Nolvadex manifested its anti-estrogen properties in the hypothalamus is stronger compared to Clomid. It was soon confirmed in animal experiments.
As a result, it was found that Clomid had on rat pituitary estrogenic effect that was significantly weaker in comparison with estradiol. In turn Nolvadex soft enough to block the action of the female hormone.
Thus, based on the results of several studies, we can say that Nolvadex exhibits a pronounced anti-estrogenic properties. The most noticeable on the effects of the drug on the HPTA axis. For bodybuilders, this fact is very important and gives a definite advantage.
It Nolvadex is able to restore the HPTA axis without compromising the pituitary sensitivity to GnRH. In turn, the application of Clomid at some point slow down the recovery of testosterone synthesis, since this must be a large number of pituitary GnRH. Read more
Besides Nolvadex is more effective in the long term, while ensuring a stable increase in the concentration of male hormone body research dianabol. Note also that Clomid globulin is able to increase the level of sex hormone binding. This will result in a lower concentration of free hormone in male versus Nolvadex.
We’re not trying to dispute the fact that both drugs are very effective anti-estrogen, able to deal with the symptoms of gynecomastia and improve the level of endogenous testosterone. But above research results prove the advantage of Nolvadex over Clomid on all counts. Buy Depo Test from Alpha Pharma dealer in USA and get it fast.
Of course, every athlete chooses for himself preparations, and the purpose of the article is not to impose their own opinions. It is a simple statement of the available scientific proven facts.